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Tissue Specific Differences in the Accumulation of Sequence Rearrangements with Age
Mitotic homologous recombination (HR) is a critical pathway for the accurate repair of DNA double strand breaks (DSBs) and broken replication forks. While generally error-free, HR can occur between misaligned sequences, resulting in deleterious sequence rearrangements that can contribute to cancer a...
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| Principais autores: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3014828/ https://ncbi.nlm.nih.gov/pubmed/18358792 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2008.01.012 |
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