Investigation of the Effects of Aging on Homologous Recombination in Long Term Bone Marrow Cultures

Fluorescent yellow direct repeat (FYDR) mice carry a transgenic reporter for homologous recombination (HR) and have been used to reveal an age dependent increase in HR in the pancreas. An established in vitro model system for accelerated aging of the marrow is the mouse long-term bone marrow culture...

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Hauptverfasser: Epperly, Michael W., Rugo, Rebecca, Cao, Shaonan, Wang, Hong, Franicola, Darcy, Goff, Julie P., Shen, Hongmei, Zhang, Xichen, Wiktor-Brown, Dominika, Engelward, Bevin P., Greenberger, Joel S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916687/
https://ncbi.nlm.nih.gov/pubmed/19779099
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