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Irradiated Esophageal Cells are Protected from Radiation-Induced Recombination by MnSOD Gene Therapy

Radiation-induced DNA damage is a precursor to mutagenesis and cytotoxicity. During radiotherapy, exposure of healthy tissues can lead to severe side effects. We explored the potential of mitochondrial SOD (MnSOD) gene therapy to protect esophageal, pancreatic and bone marrow cells from radiation-in...

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Detalhes bibliográficos
Main Authors: Niu, Yunyun, Wang, Hong, Wiktor-Brown, Dominika, Rugo, Rebecca, Shen, Hongmei, Huq, M. Saiful, Engelward, Bevin, Epperly, Michael, Greenberger, Joel S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2872095/
https://ncbi.nlm.nih.gov/pubmed/20334517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1667/RR1763.1
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