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Irradiated Esophageal Cells are Protected from Radiation-Induced Recombination by MnSOD Gene Therapy

Radiation-induced DNA damage is a precursor to mutagenesis and cytotoxicity. During radiotherapy, exposure of healthy tissues can lead to severe side effects. We explored the potential of mitochondrial SOD (MnSOD) gene therapy to protect esophageal, pancreatic and bone marrow cells from radiation-in...

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Bibliographic Details
Main Authors: Niu, Yunyun, Wang, Hong, Wiktor-Brown, Dominika, Rugo, Rebecca, Shen, Hongmei, Huq, M. Saiful, Engelward, Bevin, Epperly, Michael, Greenberger, Joel S.
Format: Artigo
Language:Inglês
Published: 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2872095/
https://ncbi.nlm.nih.gov/pubmed/20334517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1667/RR1763.1
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