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p53 Null Fluorescent Yellow Direct Repeat (FYDR) Mice have Normal Levels of Homologous Recombination
The tumor suppressor p53 is a transcription factor whose function is critical for maintaining genomic stability in mammalian cells. In response to DNA damage, p53 initiates a signaling cascade that results in cell cycle arrest, DNA repair or, if the damage is severe, programmed cell death. In additi...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3217108/ https://ncbi.nlm.nih.gov/pubmed/21993421 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2011.09.009 |
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