Identification of Four Potential Epigenetic Modulators from the NCI Structural Diversity Library Using a Cell-Based Assay

Epigenetic pathways help control the expression of genes. In cancer and other diseases, aberrant silencing or overexpression of genes, such as those that control cell growth, can greatly contribute to pathogenesis. Access to these genes by the transcriptional machinery is largely mediated by chemica...

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Detalhes bibliográficos
Main Authors: Best, Anne M., Chang, Jianjun, Dull, Angie B., Beutler, John A., Martinez, Elisabeth D.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3014726/
https://ncbi.nlm.nih.gov/pubmed/21234371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/868095
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