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Composition and applications of focus libraries to phenotypic assays

The wealth of bioactivity information now available on low-molecular weight compounds has enabled a paradigm shift in chemical biology and early phase drug discovery efforts. Traditionally chemical libraries have been most commonly employed in screening approaches where a bioassay is used to charact...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Wassermann, Anne Mai, Camargo, Luiz M., Auld, Douglas S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4109565/
https://ncbi.nlm.nih.gov/pubmed/25104937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2014.00164
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