National Cancer Institute (NCI) Program for Natural Products Discovery: Rapid Isolation and Identification of Biologically Active Natural Products from the NCI Prefractionated Library

[Image: see text] An automated, high-capacity, and high-throughput procedure for the rapid isolation and identification of biologically active natural products from a prefractionated library is presented. The semipreparative HPLC method uses 1 mg of the primary hit fraction and produces 22 subfracti...

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Detalhes bibliográficos
Publicado no:ACS Chem Biol
Main Authors: Grkovic, Tanja, Akee, Rhone K., Thornburg, Christopher C., Trinh, Spencer K., Britt, John R., Harris, Matthew J., Evans, Jason R., Kang, Unwoo, Ensel, Susan, Henrich, Curtis J., Gustafson, Kirk R., Schneider, Joel P., O’Keefe, Barry R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2020
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7171602/
https://ncbi.nlm.nih.gov/pubmed/32223208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.0c00139
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