National Cancer Institute (NCI) Program for Natural Products Discovery: Rapid Isolation and Identification of Biologically Active Natural Products from the NCI Prefractionated Library

[Image: see text] An automated, high-capacity, and high-throughput procedure for the rapid isolation and identification of biologically active natural products from a prefractionated library is presented. The semipreparative HPLC method uses 1 mg of the primary hit fraction and produces 22 subfracti...

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Veröffentlicht in:ACS Chem Biol
Hauptverfasser: Grkovic, Tanja, Akee, Rhone K., Thornburg, Christopher C., Trinh, Spencer K., Britt, John R., Harris, Matthew J., Evans, Jason R., Kang, Unwoo, Ensel, Susan, Henrich, Curtis J., Gustafson, Kirk R., Schneider, Joel P., O’Keefe, Barry R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Chemical Society 2020
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7171602/
https://ncbi.nlm.nih.gov/pubmed/32223208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.0c00139
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