National Cancer Institute (NCI) Program for Natural Products Discovery: Rapid Isolation and Identification of Biologically Active Natural Products from the NCI Prefractionated Library

[Image: see text] An automated, high-capacity, and high-throughput procedure for the rapid isolation and identification of biologically active natural products from a prefractionated library is presented. The semipreparative HPLC method uses 1 mg of the primary hit fraction and produces 22 subfracti...

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Bibliografski detalji
Izdano u:ACS Chem Biol
Glavni autori: Grkovic, Tanja, Akee, Rhone K., Thornburg, Christopher C., Trinh, Spencer K., Britt, John R., Harris, Matthew J., Evans, Jason R., Kang, Unwoo, Ensel, Susan, Henrich, Curtis J., Gustafson, Kirk R., Schneider, Joel P., O’Keefe, Barry R.
Format: Artigo
Jezik:Inglês
Izdano: American Chemical Society 2020
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7171602/
https://ncbi.nlm.nih.gov/pubmed/32223208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.0c00139
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