National Cancer Institute (NCI) Program for Natural Products Discovery: Rapid Isolation and Identification of Biologically Active Natural Products from the NCI Prefractionated Library

[Image: see text] An automated, high-capacity, and high-throughput procedure for the rapid isolation and identification of biologically active natural products from a prefractionated library is presented. The semipreparative HPLC method uses 1 mg of the primary hit fraction and produces 22 subfracti...

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Bibliografiske detaljer
Udgivet i:ACS Chem Biol
Main Authors: Grkovic, Tanja, Akee, Rhone K., Thornburg, Christopher C., Trinh, Spencer K., Britt, John R., Harris, Matthew J., Evans, Jason R., Kang, Unwoo, Ensel, Susan, Henrich, Curtis J., Gustafson, Kirk R., Schneider, Joel P., O’Keefe, Barry R.
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2020
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7171602/
https://ncbi.nlm.nih.gov/pubmed/32223208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.0c00139
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