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Lineage tracing reveals the dynamic contribution of Hes1(+) cells to the developing and adult pancreas

Notch signaling regulates numerous developmental processes, often acting either to promote one cell fate over another or else to inhibit differentiation altogether. In the embryonic pancreas, Notch and its target gene Hes1 are thought to inhibit endocrine and exocrine specification. Although differe...

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Bibliografische gegevens
Hoofdauteurs: Kopinke, Daniel, Brailsford, Marisa, Shea, Jill E., Leavitt, Rebecca, Scaife, Courtney L., Murtaugh, L. Charles
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Company of Biologists 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3014632/
https://ncbi.nlm.nih.gov/pubmed/21205788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.053843
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