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Exocrine-to-endocrine differentiation is detectable only prior to birth in the uninjured mouse pancreas

BACKGROUND: Histological evidence suggests that insulin-producing beta (β)-cells arise in utero from duct-like structures of the fetal exocrine pancreas, and genetic lineage tracing studies indicate that they are maintained in the adult by self-renewal. These studies have not addressed the origin of...

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Hlavní autoři: Kopinke, Daniel, Murtaugh, L Charles
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2858732/
https://ncbi.nlm.nih.gov/pubmed/20377894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-213X-10-38
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