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Exocrine-to-endocrine differentiation is detectable only prior to birth in the uninjured mouse pancreas

BACKGROUND: Histological evidence suggests that insulin-producing beta (β)-cells arise in utero from duct-like structures of the fetal exocrine pancreas, and genetic lineage tracing studies indicate that they are maintained in the adult by self-renewal. These studies have not addressed the origin of...

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Detalhes bibliográficos
Main Authors: Kopinke, Daniel, Murtaugh, L Charles
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2858732/
https://ncbi.nlm.nih.gov/pubmed/20377894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-213X-10-38
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