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Ongoing Notch signaling maintains phenotypic fidelity in the adult exocrine pancreas

The Notch signaling pathway regulates embryonic development of the pancreas, inhibiting progenitor differentiation into exocrine acinar and endocrine islet cells. The adult pancreas appears to lack progenitor cells, and its mature cell types are maintained by the proliferation of pre-existing differ...

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Detalhes bibliográficos
Main Authors: Kopinke, Daniel, Brailsford, Marisa, Pan, Fong Cheng, Magnuson, Mark A., Wright, Christopher V.E., Murtaugh, L. Charles
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3254730/
https://ncbi.nlm.nih.gov/pubmed/22146645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2011.11.010
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