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Lineage tracing reveals the dynamic contribution of Hes1(+) cells to the developing and adult pancreas
Notch signaling regulates numerous developmental processes, often acting either to promote one cell fate over another or else to inhibit differentiation altogether. In the embryonic pancreas, Notch and its target gene Hes1 are thought to inhibit endocrine and exocrine specification. Although differe...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Company of Biologists
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3014632/ https://ncbi.nlm.nih.gov/pubmed/21205788 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.053843 |
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