A New Model of Epstein-Barr Virus Infection Reveals an Important Role for Early Lytic Viral Protein Expression in the Development of Lymphomas

Epstein-Barr virus (EBV) infects cells in latent or lytic forms, but the role of lytic infection in EBV-induced lymphomas is unclear. Here, we have used a new humanized mouse model, in which both human fetal CD34(+) hematopoietic stem cells and thymus/liver tissue are transplanted, to compare EBV pa...

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Hlavní autoři: Ma, Shi-Dong, Hegde, Subramanya, Young, Ken H., Sullivan, Ruth, Rajesh, Deepika, Zhou, Ying, Jankowska-Gan, Ewa, Burlingham, William J., Sun, Xiaoping, Gulley, Margaret L., Tang, Weihua, Gumperz, Jenny E., Kenney, Shannon C.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2011
Témata:
Pathogenesis and Immunity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3014199/
https://ncbi.nlm.nih.gov/pubmed/20980506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01512-10
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