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Antiviral Effects of a Transgenic RNA-Dependent RNA Polymerase
Transgenic expression of the RNA-dependent RNA polymerase 3D(pol) inhibited infection of Theiler's murine encephalitis virus (TMEV), a picornavirus from which it was derived. Here, we infected 3D(pol) transgenic mice with another picornavirus, as well as an alphaherpesvirus and a rhabdovirus. 3...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology (ASM)
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3014166/ https://ncbi.nlm.nih.gov/pubmed/20962089 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01626-10 |
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