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Transgenic Expression of the 3D Polymerase Inhibits Theiler's Virus Infection and Demyelination

The RNA-dependent RNA polymerase 3D(pol) is required for the elongation of positive- and negative-stranded picornavirus RNA. During the course of investigating the effect of the transgenic expression of viral genes on the host immune response, we evaluated the viral load present in the host after in...

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Detalhes bibliográficos
Main Authors: Kerkvliet, Jason, Zoecklein, Laurie, Papke, Louisa, Denic, Aleksandar, Bieber, Allan J., Pease, Larry R., David, Chella S., Rodriguez, Moses
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786735/
https://ncbi.nlm.nih.gov/pubmed/19759133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00664-09
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