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Transgenic Expression of Viral Capsid Proteins Predisposes to Axonal Injury in a Murine Model of Multiple Sclerosis

We used transgenic expression of capsid antigens to Theiler's murine encephalomyelitis virus (TMEV) to study the influence of VP1, VP2 or VP2(121–130) to either protection or pathogenesis to chronic spinal cord demyelination, axonal loss and functional deficits during the acute and chronic phas...

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Main Authors: Denic, Aleksandar, Zoecklein, Laurie, Kerkvliet, Jason, Papke, Louisa, Edukulla, Ramakrishna, Warrington, Arthur, Bieber, Allan, Pease, Larry R., David, Chella S., Rodriguez, Moses
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Publishing Ltd 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3139028/
https://ncbi.nlm.nih.gov/pubmed/21314744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.2011.00474.x
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