Transgenic Expression of the 3D Polymerase Inhibits Theiler's Virus Infection and Demyelination

The RNA-dependent RNA polymerase 3D(pol) is required for the elongation of positive- and negative-stranded picornavirus RNA. During the course of investigating the effect of the transgenic expression of viral genes on the host immune response, we evaluated the viral load present in the host after in...

Full description

Saved in:
Bibliographic Details
Main Authors: Kerkvliet, Jason, Zoecklein, Laurie, Papke, Louisa, Denic, Aleksandar, Bieber, Allan J., Pease, Larry R., David, Chella S., Rodriguez, Moses
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2009
Subjects:
Pathogenesis and Immunity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786735/
https://ncbi.nlm.nih.gov/pubmed/19759133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00664-09
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items