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Novel Roles of the Picornaviral 3D Polymerase in Viral Pathogenesis
The RNA-dependent RNA-polymerase, 3D(pol), is an essential component in the picornavirus genome for the replication of single stranded RNA. However, transgenic expression of 3D(pol) in mice has antiviral effects. Here, we discuss the structure and function of 3D(pol) during picornavirus replication,...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Hindawi Publishing Corporation
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2897181/ https://ncbi.nlm.nih.gov/pubmed/20625447 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2010/368068 |
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