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Smad2 Protects against TGF-β/Smad3-Mediated Renal Fibrosis
Smad2 and Smad3 interact and mediate TGF-β signaling. Although Smad3 promotes fibrosis, the role of Smad2 in fibrogenesis is largely unknown. In this study, conditional deletion of Smad2 from the kidney tubular epithelial cells markedly enhanced fibrosis in response to unilateral ureteral obstructio...
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| Hlavní autoři: | , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society of Nephrology
2010
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3013519/ https://ncbi.nlm.nih.gov/pubmed/20595680 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2009121244 |
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