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Unraveling the Binding Mechanism of Trivalent Tumor Necrosis Factor Ligands and Their Receptors
Characterization of the binding of a tumor necrosis factor (TNF) ligand to its receptor(s) is pivotal to understand how these proteins initiate signal transduction pathways. Unfortunately, kinetic elucidation of these interactions is strongly hampered by the multivalent nature of the binding partner...
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| Główni autorzy: | , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
The American Society for Biochemistry and Molecular Biology
2011
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3013454/ https://ncbi.nlm.nih.gov/pubmed/20852190 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M110.002808 |
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