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Silanetriols as in vitro inhibitors for AChE

Three stable silanetriols with increasing steric protection of the silicon atom have been tested for inhibition of acetylcholinesterase (AChE). For all tested silanetriols we found reversible inhibition of the AChE activity at a 100 μM concentration. The highest inhibition rate was found for the ste...

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Detalles Bibliográficos
Main Authors: Blunder, Martina, Hurkes, Natascha, Spirk, Stefan, List, Martina, Pietschnig, Rudolf
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier Science Ltd 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3013380/
https://ncbi.nlm.nih.gov/pubmed/21111617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2010.10.139
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