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Neuronal AChE splice variants and their non-hydrolytic functions: redefining a target of AChE inhibitors?
AChE enzymatic inhibition is a core focus of pharmacological intervention in Alzheimer's disease (AD). Yet, AChE has also been ascribed non-hydrolytic functions, which seem related to its appearance in various isoforms. Neuronal AChE presents as a tailed form (AChE-T) predominantly found on the...
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| Autor principal: | |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell publishing Ltd
2013
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3949645/ https://ncbi.nlm.nih.gov/pubmed/23991627 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12359 |
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