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Baicalein as a Potential Inhibitor against BACE1 and AChE: Mechanistic Comprehension through In Vitro and Computational Approaches

One of the major neurodegenerative features of Alzheimer’s disease (AD) is the presence of neurotoxic amyloid plaques composed of amyloid beta peptide (Aβ). β-Secretase (BACE1) and acetylcholinesterase (AChE), which promote Aβ fibril formation, have become attractive therapeutic targets for AD. P-gl...

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Bibliografske podrobnosti
izdano v:Nutrients
Main Authors: Han, Jin, Ji, Yeongseon, Youn, Kumju, Lim, GyuTae, Lee, Jinhyuk, Kim, Dong Hyun, Jun, Mira
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6893645/
https://ncbi.nlm.nih.gov/pubmed/31703329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nu11112694
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