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Baicalein as a Potential Inhibitor against BACE1 and AChE: Mechanistic Comprehension through In Vitro and Computational Approaches

One of the major neurodegenerative features of Alzheimer’s disease (AD) is the presence of neurotoxic amyloid plaques composed of amyloid beta peptide (Aβ). β-Secretase (BACE1) and acetylcholinesterase (AChE), which promote Aβ fibril formation, have become attractive therapeutic targets for AD. P-gl...

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Podrobná bibliografie
Vydáno v:Nutrients
Hlavní autoři: Han, Jin, Ji, Yeongseon, Youn, Kumju, Lim, GyuTae, Lee, Jinhyuk, Kim, Dong Hyun, Jun, Mira
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6893645/
https://ncbi.nlm.nih.gov/pubmed/31703329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nu11112694
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