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Sphingosine 1-phosphate receptor-2 function in myeloid cells regulates vascular inflammation and atherosclerosis
OBJECTIVE: Sphingomyelin deposition and metabolism occurs in the atherosclerotic plaque, leading to the formation of sphingosine 1-phosphate (S1P), which activates G protein-coupled receptors to regulate vascular and immune cells. The role of S1P receptors in atherosclerosis has not been examined. M...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3013369/ https://ncbi.nlm.nih.gov/pubmed/20947824 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.110.213496 |
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