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Sphingosine 1-phosphate receptor-2 function in myeloid cells regulates vascular inflammation and atherosclerosis

OBJECTIVE: Sphingomyelin deposition and metabolism occurs in the atherosclerotic plaque, leading to the formation of sphingosine 1-phosphate (S1P), which activates G protein-coupled receptors to regulate vascular and immune cells. The role of S1P receptors in atherosclerosis has not been examined. M...

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Detalhes bibliográficos
Main Authors: Skoura, Athanasia, Michaud, Jason, Im, Dong-Soon, Thangada, Shobha, Xiong, Yuquan, Smith, Jonathan, Hla, Timothy
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3013369/
https://ncbi.nlm.nih.gov/pubmed/20947824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.110.213496
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