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Vascular Endothelium As a Contributor of Plasma Sphingosine 1-Phosphate

Sphingosine 1-phosphate (S1P), an abundant lipid mediator in plasma, regulates vascular and immune cells by activating S1P receptors. In this report, we investigated the mechanisms by which high plasma S1P levels are maintained in mice. We found that plasma S1P turns over rapidly with a half-life of...

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Autori principali: Venkataraman, Krishnan, Lee, Yong-Moon, Michaud, Jason, Thangada, Shobha, Ai, Youxi, Bonkovsky, Herbert L., Parikh, Nehal S., Habrukowich, Cheryl, Hla, Timothy
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2659392/
https://ncbi.nlm.nih.gov/pubmed/18258856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.107.165845
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