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Vascular Endothelium As a Contributor of Plasma Sphingosine 1-Phosphate

Sphingosine 1-phosphate (S1P), an abundant lipid mediator in plasma, regulates vascular and immune cells by activating S1P receptors. In this report, we investigated the mechanisms by which high plasma S1P levels are maintained in mice. We found that plasma S1P turns over rapidly with a half-life of...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Venkataraman, Krishnan, Lee, Yong-Moon, Michaud, Jason, Thangada, Shobha, Ai, Youxi, Bonkovsky, Herbert L., Parikh, Nehal S., Habrukowich, Cheryl, Hla, Timothy
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2659392/
https://ncbi.nlm.nih.gov/pubmed/18258856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.107.165845
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