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Vascular Endothelium As a Contributor of Plasma Sphingosine 1-Phosphate

Sphingosine 1-phosphate (S1P), an abundant lipid mediator in plasma, regulates vascular and immune cells by activating S1P receptors. In this report, we investigated the mechanisms by which high plasma S1P levels are maintained in mice. We found that plasma S1P turns over rapidly with a half-life of...

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Detalhes bibliográficos
Main Authors: Venkataraman, Krishnan, Lee, Yong-Moon, Michaud, Jason, Thangada, Shobha, Ai, Youxi, Bonkovsky, Herbert L., Parikh, Nehal S., Habrukowich, Cheryl, Hla, Timothy
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2659392/
https://ncbi.nlm.nih.gov/pubmed/18258856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.107.165845
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