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Extracellular export of sphingosine kinase-1a contributes to the vascular S1P gradient

Sphingosine 1-phosphate (S1P), produced by Sphks (sphingosine kinases), is a multifunctional lipid mediator that regulates immune cell trafficking and vascular development. Mammals maintain a large concentration gradient of S1P between vascular and extravascular compartments. Mechanisms by which S1P...

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Bibliografiska uppgifter
Huvudupphovsmän: Venkataraman, Krishnan, Thangada, Shobha, Michaud, Jason, Oo, Myat Lin, Ai, Youxi, Lee, Yong-Moon, Wu, Mingtao, Parikh, Nehal S., Khan, Faraz, Proia, Richard L., Hla, Timothy
Materialtyp: Artigo
Språk:Inglês
Publicerad: Portland Press Ltd. 2006
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1533315/
https://ncbi.nlm.nih.gov/pubmed/16623665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20060251
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