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The human mitochondrial deoxynucleotide carrier and its role in the toxicity of nucleoside antivirals
The synthesis of DNA in mitochondria requires the uptake of deoxynucleotides into the matrix of the organelle. We have characterized a human cDNA encoding a member of the family of mitochondrial carriers. The protein has been overexpressed in bacteria and reconstituted into phospholipid vesicles whe...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The National Academy of Sciences
2001
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC30130/ https://ncbi.nlm.nih.gov/pubmed/11226231 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.031430998 |
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