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The human mitochondrial deoxynucleotide carrier and its role in the toxicity of nucleoside antivirals

The synthesis of DNA in mitochondria requires the uptake of deoxynucleotides into the matrix of the organelle. We have characterized a human cDNA encoding a member of the family of mitochondrial carriers. The protein has been overexpressed in bacteria and reconstituted into phospholipid vesicles whe...

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Bibliografski detalji
Glavni autori: Dolce, Vincenza, Fiermonte, Giuseppe, Runswick, Michael J., Palmieri, Ferdinando, Walker, John E.
Format: Artigo
Jezik:Inglês
Izdano: The National Academy of Sciences 2001
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC30130/
https://ncbi.nlm.nih.gov/pubmed/11226231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.031430998
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