The ARF Tumor Suppressor Regulates Bone Remodeling and Osteosarcoma Development in Mice

The ARF tumor suppressor regulates p53 as well as basic developmental processes independent of p53, including osteoclast activation, by controlling ribosomal biogenesis. Here we provide evidence that ARF is a master regulator of bone remodeling and osteosarcoma (OS) development in mice. Arf(-/-) mic...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Rauch, Daniel A., Hurchla, Michelle A., Harding, John C., Deng, Hongju, Shea, Lauren K., Eagleton, Mark C., Niewiesk, Stefan, Lairmore, Michael D., Piwnica-Worms, David, Rosol, Thomas J., Weber, Jason D., Ratner, Lee, Weilbaecher, Katherine N.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Public Library of Science 2010
विषय:
Research Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3012707/
https://ncbi.nlm.nih.gov/pubmed/21209895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015755
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