Serum immunoglobulin free light-chain measurement in primary amyloidosis: prognostic value and correlations with clinical features

Immunoglobulin free light chains (FLCs) are the precursors of amyloid fibrils in primary amyloidosis (AL). We studied the relationship between FLC levels and clinical features in 730 patients with newly diagnosed AL. The plasma cell clone was λ in 72% patients, and κ in 28% patients. κ-AL had more G...

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Autors principals: Kumar, Shaji, Dispenzieri, Angela, Katzmann, Jerry A., Larson, Dirk R., Colby, Colin L., Lacy, Martha Q., Hayman, Suzanne R., Buadi, Francis K., Leung, Nelson, Zeldenrust, Steve R., Ramirez-Alvarado, Marina, Clark, Raynell J., Kyle, Robert A., Rajkumar, S. Vincent, Gertz, Morie A.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2010
Matèries:
Clinical Trials and Observations
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3012533/
https://ncbi.nlm.nih.gov/pubmed/20798235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-06-290668
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