Serum immunoglobulin free light-chain measurement in primary amyloidosis: prognostic value and correlations with clinical features

Immunoglobulin free light chains (FLCs) are the precursors of amyloid fibrils in primary amyloidosis (AL). We studied the relationship between FLC levels and clinical features in 730 patients with newly diagnosed AL. The plasma cell clone was λ in 72% patients, and κ in 28% patients. κ-AL had more G...

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Bibliographic Details
Main Authors: Kumar, Shaji, Dispenzieri, Angela, Katzmann, Jerry A., Larson, Dirk R., Colby, Colin L., Lacy, Martha Q., Hayman, Suzanne R., Buadi, Francis K., Leung, Nelson, Zeldenrust, Steve R., Ramirez-Alvarado, Marina, Clark, Raynell J., Kyle, Robert A., Rajkumar, S. Vincent, Gertz, Morie A.
Format: Artigo
Language:Inglês
Published: American Society of Hematology 2010
Subjects:
Clinical Trials and Observations
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3012533/
https://ncbi.nlm.nih.gov/pubmed/20798235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-06-290668
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