Serum immunoglobulin free light-chain measurement in primary amyloidosis: prognostic value and correlations with clinical features

Immunoglobulin free light chains (FLCs) are the precursors of amyloid fibrils in primary amyloidosis (AL). We studied the relationship between FLC levels and clinical features in 730 patients with newly diagnosed AL. The plasma cell clone was λ in 72% patients, and κ in 28% patients. κ-AL had more G...

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Main Authors: Kumar, Shaji, Dispenzieri, Angela, Katzmann, Jerry A., Larson, Dirk R., Colby, Colin L., Lacy, Martha Q., Hayman, Suzanne R., Buadi, Francis K., Leung, Nelson, Zeldenrust, Steve R., Ramirez-Alvarado, Marina, Clark, Raynell J., Kyle, Robert A., Rajkumar, S. Vincent, Gertz, Morie A.
格式: Artigo
語言:Inglês
出版: American Society of Hematology 2010
主題:
Clinical Trials and Observations
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3012533/
https://ncbi.nlm.nih.gov/pubmed/20798235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-06-290668
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