Serum immunoglobulin free light-chain measurement in primary amyloidosis: prognostic value and correlations with clinical features

Immunoglobulin free light chains (FLCs) are the precursors of amyloid fibrils in primary amyloidosis (AL). We studied the relationship between FLC levels and clinical features in 730 patients with newly diagnosed AL. The plasma cell clone was λ in 72% patients, and κ in 28% patients. κ-AL had more G...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Kumar, Shaji, Dispenzieri, Angela, Katzmann, Jerry A., Larson, Dirk R., Colby, Colin L., Lacy, Martha Q., Hayman, Suzanne R., Buadi, Francis K., Leung, Nelson, Zeldenrust, Steve R., Ramirez-Alvarado, Marina, Clark, Raynell J., Kyle, Robert A., Rajkumar, S. Vincent, Gertz, Morie A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society of Hematology 2010
Gaiak:
Clinical Trials and Observations
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3012533/
https://ncbi.nlm.nih.gov/pubmed/20798235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-06-290668
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