CBP gene transfer increases BDNF levels and ameliorates learning and memory deficits in a mouse model of Alzheimer's disease

Cognitive dysfunction and memory loss are common features of Alzheimer's disease (AD). Abnormalities in the expression profile of immediate early genes that play a critical role in memory formation, such as the cAMP-response element binding protein (CREB), have been reported in the brains of AD...

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Main Authors: Caccamo, Antonella, Maldonado, Monica A., Bokov, Alex F., Majumder, Smita, Oddo, Salvatore
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2010
主題:
Biological Sciences
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3012497/
https://ncbi.nlm.nih.gov/pubmed/21149712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1012851108
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