Bcr/Abl Interferes with the Fanconi Anemia/BRCA Pathway: Implications in the Chromosomal Instability of Chronic Myeloid Leukemia Cells

Chronic myeloid leukemia (CML) is a malignant clonal disorder of the hematopoietic system caused by the expression of the BCR/ABL fusion oncogene. Although it is well known that CML cells are genetically unstable, the mechanisms accounting for this genomic instability are still poorly understood. Be...

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Hlavní autoři: Valeri, Antonio, Alonso-Ferrero, Maria Eugenia, Río, Paula, Pujol, María Roser, Casado, José A., Pérez, Laura, Jacome, Ariana, Agirre, Xabier, Calasanz, Maria José, Hanenberg, Helmut, Surrallés, Jordi, Prosper, Felipe, Albella, Beatriz, Bueren, Juan A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2010
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3011007/
https://ncbi.nlm.nih.gov/pubmed/21203397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015525
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