Bcr/Abl Interferes with the Fanconi Anemia/BRCA Pathway: Implications in the Chromosomal Instability of Chronic Myeloid Leukemia Cells

Chronic myeloid leukemia (CML) is a malignant clonal disorder of the hematopoietic system caused by the expression of the BCR/ABL fusion oncogene. Although it is well known that CML cells are genetically unstable, the mechanisms accounting for this genomic instability are still poorly understood. Be...

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Autors principals: Valeri, Antonio, Alonso-Ferrero, Maria Eugenia, Río, Paula, Pujol, María Roser, Casado, José A., Pérez, Laura, Jacome, Ariana, Agirre, Xabier, Calasanz, Maria José, Hanenberg, Helmut, Surrallés, Jordi, Prosper, Felipe, Albella, Beatriz, Bueren, Juan A.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2010
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3011007/
https://ncbi.nlm.nih.gov/pubmed/21203397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015525
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