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Molecular Basis of Differential B-Pentamer Stability of Shiga Toxins 1 and 2

Escherichia coli strain O157:H7 is a major cause of food poisoning that can result in severe diarrhea and, in some cases, renal failure. The pathogenesis of E. coli O157:H7 is in large part due to the production of Shiga toxin (Stx), an AB(5) toxin that consists of a ribosomal RNA-cleaving A-subunit...

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Detalhes bibliográficos
Main Authors: Conrady, Deborah G., Flagler, Michael J., Friedmann, David R., Vander Wielen, Bradley D., Kovall, Rhett A., Weiss, Alison A., Herr, Andrew B.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3010993/
https://ncbi.nlm.nih.gov/pubmed/21203383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015153
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