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Shiga Toxin Binding to Glycolipids and Glycans

BACKGROUND: Immunologically distinct forms of Shiga toxin (Stx1 and Stx2) display different potencies and disease outcomes, likely due to differences in host cell binding. The glycolipid globotriaosylceramide (Gb3) has been reported to be the receptor for both toxins. While there is considerable dat...

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Autors principals: Gallegos, Karen M., Conrady, Deborah G., Karve, Sayali S., Gunasekera, Thusitha S., Herr, Andrew B., Weiss, Alison A.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3278406/
https://ncbi.nlm.nih.gov/pubmed/22348006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030368
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