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Intestinal organoids model human responses to infection by commensal and Shiga toxin producing Escherichia coli

Infection with Shiga toxin (Stx) producing Escherichia coli O157:H7 can cause the potentially fatal complication hemolytic uremic syndrome, and currently only supportive therapy is available. Lack of suitable animal models has hindered study of this disease. Induced human intestinal organoids (iHIOs...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Karve, Sayali S., Pradhan, Suman, Ward, Doyle V., Weiss, Alison A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5470682/
https://ncbi.nlm.nih.gov/pubmed/28614372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0178966
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