Tissue Responses to Shiga Toxin in Human Intestinal Organoids

BACKGROUND & AIMS: Shiga toxin (Stx)-producing Escherichia coli (eg, O157:H7) infection produces bloody diarrhea, while Stx inhibits protein synthesis and causes the life-threatening systemic complication of hemolytic uremic syndrome. The murine intestinal tract is resistant to O157:H7 and Stx,...

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Bibliografiske detaljer
Udgivet i:Cell Mol Gastroenterol Hepatol
Main Authors: Pradhan, Suman, Karve, Sayali S., Weiss, Alison A., Hawkins, Jennifer, Poling, Holly M., Helmrath, Michael A., Wells, James M., McCauley, Heather A.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2020
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7240222/
https://ncbi.nlm.nih.gov/pubmed/32145469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2020.02.006
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