Ligand-Induced Tyrosine Phosphorylation of Cysteinyl Leukotriene Receptor 1 Triggers Internalization and Signaling in Intestinal Epithelial Cells

BACKGROUND: Leukotriene D(4) (LTD(4)) belongs to the bioactive lipid group known as eicosanoids and has implications in pathological processes such as inflammation and cancer. Leukotriene D(4) exerts its effects mainly through two different G-protein-coupled receptors, CysLT(1) and CysLT(2). The hig...

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Main Authors: Parhamifar, Ladan, Sime, Wondossen, Yudina, Yuliana, Vilhardt, Frederik, Mörgelin, Matthias, Sjölander, Anita
格式: Artigo
語言:Inglês
出版: Public Library of Science 2010
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Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3010979/
https://ncbi.nlm.nih.gov/pubmed/21203429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014439
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