Ligand-Induced Tyrosine Phosphorylation of Cysteinyl Leukotriene Receptor 1 Triggers Internalization and Signaling in Intestinal Epithelial Cells

BACKGROUND: Leukotriene D(4) (LTD(4)) belongs to the bioactive lipid group known as eicosanoids and has implications in pathological processes such as inflammation and cancer. Leukotriene D(4) exerts its effects mainly through two different G-protein-coupled receptors, CysLT(1) and CysLT(2). The hig...

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Autori principali: Parhamifar, Ladan, Sime, Wondossen, Yudina, Yuliana, Vilhardt, Frederik, Mörgelin, Matthias, Sjölander, Anita
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2010
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3010979/
https://ncbi.nlm.nih.gov/pubmed/21203429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014439
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