Ligand-Induced Tyrosine Phosphorylation of Cysteinyl Leukotriene Receptor 1 Triggers Internalization and Signaling in Intestinal Epithelial Cells

BACKGROUND: Leukotriene D(4) (LTD(4)) belongs to the bioactive lipid group known as eicosanoids and has implications in pathological processes such as inflammation and cancer. Leukotriene D(4) exerts its effects mainly through two different G-protein-coupled receptors, CysLT(1) and CysLT(2). The hig...

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Autors principals: Parhamifar, Ladan, Sime, Wondossen, Yudina, Yuliana, Vilhardt, Frederik, Mörgelin, Matthias, Sjölander, Anita
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2010
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3010979/
https://ncbi.nlm.nih.gov/pubmed/21203429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014439
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