Wnt5a regulates directional cell migration and cell proliferation via Ror2-mediated noncanonical pathway in mammalian palate development

Tissue and molecular heterogeneities are present in the developing secondary palate along the anteroposterior (AP) axis in mice. Here, we show that Wnt5a and its receptor Ror2 are expressed in a graded manner along the AP axis of the palate. Wnt5a deficiency leads to a complete cleft of the secondar...

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Main Authors: He, Fenglei, Xiong, Wei, Yu, Xueyan, Espinoza-Lewis, Ramon, Liu, Chao, Gu, Shuping, Nishita, Michiru, Suzuki, Kentaro, Yamada, Gen, Minami, Yasuhiro, Chen, YiPing
Format: Artigo
Jezik:Inglês
Izdano: 2008
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3010758/
https://ncbi.nlm.nih.gov/pubmed/18948417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.025767
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