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CD8(+) T cells negatively regulate IL-4-dependent, IgG1-dominant post-transplant alloantibody production

We have previously reported that CD8(+) T cells significantly influence antibody production based on the observation that post-transplant alloantibody levels in CD8-deficient murine hepatocyte transplant recipients are markedly enhanced. However, the precise mechanism(s) contributing to enhanced all...

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Autori principali: Zimmerer, Jason M., Pham, Thomas A., Sanders, Virginia M., Bumgardner, Ginny L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3010751/
https://ncbi.nlm.nih.gov/pubmed/21084663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1001655
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