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Alloprimed CD8(+) T cells Regulate Alloantibody and Eliminate Alloprimed B cells through Perforin- and FasL-dependent mechanisms

While it is well known that CD4(+) T cells and B cells collaborate for antibody production, our group previously reported that CD8(+) T cells downregulate alloantibody responses following transplantation. However, the exact mechanism involved in CD8(+) T cell-mediated downregulation of alloantibody...

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Detalhes bibliográficos
Main Authors: Zimmerer, J.M., Pham, T.A., Wright, C.L., Tobin, K.J., Sanghavi, P.B., Elzein, S.M., Sanders, V.M., Bumgardner, G.L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4018729/
https://ncbi.nlm.nih.gov/pubmed/24472191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.12565
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