Wird geladen...
mTOR Inhibition Suppresses Posttransplant Alloantibody Production through Direct Inhibition of Alloprimed B cells and Sparing of CD8(+) antibody-suppressing T cells
BACKGROUND: De novo alloantibodies (DSA) contribute to antibody-mediated rejection and poor long-term graft survival. Since the development of DSA is associated with early graft loss of cell transplants and reduced long-term survival of solid organ transplants, we hypothesized that conventional immu...
Gespeichert in:
| Veröffentlicht in: | Transplantation |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
|
| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4992451/ https://ncbi.nlm.nih.gov/pubmed/27362313 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TP.0000000000001291 |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|