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Cytotoxic effector function of CD4-independent, CD8(+) T cells is mediated by TNF-α/TNFR
BACKGROUND: Liver parenchymal cell allografts initiate both CD4-dependent and CD4-independent, CD8(+) T cell-mediated acute rejection pathways. The magnitude of allospecific CD8(+) T cell in vivo cytotoxic effector function is maximal when primed in the presence of CD4(+) T cells. The current studie...
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Main Authors: | , , , , , , |
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格式: | Artigo |
語言: | Inglês |
出版: |
2012
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主題: | |
在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3522862/ https://ncbi.nlm.nih.gov/pubmed/23222736 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TP.0b013e318270f3c0 |
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